Publications 1

List of selected publications:

Prof. Jürgen Behrens

Miete C, Solis GP, Koval A, Brückner M, Katanaev VL, Behrens J, Bernkopf DB. (2022)
Gαi2-induced conductin/axin2 condensates inhibit Wnt/β-catenin signaling and suppress cancer growth. Nat CommunBernkopf

DB, Brückner M, Hadjihannas MV, Behrens J. (2019)
An aggregon in conductin/axin2 regulates Wnt/β-catenin signaling and holds potential for cancer therapy. J. Nat Commun.

Unterer, B., Wiesmann, V., Gunasekaran, M., Sticht, H., Tenkerian, C., Behrens, J., Leone, M., Engel, F.B., Britzen-Laurent, N., Naschberger, E., et al. (2018).
IFN-gamma-response mediator GBP-1 represses human cell proliferation by inhibiting the Hippo signaling transcription factor TEAD. Biochem J.

Comai, G., Boutet, A., Tanneberger, K., Massa, F., Rocha, A.S., Charlet, A., Panzolini, C., Motamedi, F.J., Brommage, R., Hans, W., et al. (2018).
Genetic and molecular insights into genotype-phenotype relationships in osteopathia striata with cranial sclerosis (OSCS) through the analysis of novel mouse Wtx mutant alleles. J Bone Miner Res.

Bernkopf, D.B., Jalal, K., Bruckner, M., Knaup, K.X., Gentzel, M., Schambony, A., and Behrens, J. (2018).
Pgam5 released from damaged mitochondria induces mitochondrial biogenesis via Wnt signaling. J Cell Biol.

Bernkopf, D.B., Daum, G., Bruckner, M., and Behrens, J. (2018).
Sulforaphane inhibits growth and blocks Wnt/beta-catenin signaling of colorectal cancer cells. Oncotarget.

Bernkopf, D.B., and Behrens, J. (2018).
Cell intrinsic Wnt/beta-catenin signaling activation. Aging (Albany NY).

Bernkopf, D.B., and Behrens, J. (2018).
Feedback regulation of mitochondrial homeostasis via Wnt/beta-catenin signaling. Mol Cell Oncol.

Rauschenberger, V., Bernkopf, D.B., Krenn, S., Jalal, K., Heller, J., Behrens, J., Gentzel, M., and Schambony, A. (2017).
The phosphatase Pgam5 antagonizes Wnt/beta-Catenin signaling in embryonic anterior-posterior axis patterning. Development.

Mishra, H.K., Prots, I., Havlicek, S., Kohl, Z., Perez-Branguli, F., Boerstler, T., Anneser, L., Minakaki, G., Wend, H., Hampl, M., et al. (2016).
GSK3β-Dependent Dysregulation of Neurodevelopment in SPG11-Patient Induced Pluripotent Stem Cell Model. Ann. Neurol.

Huraskin, D., Eiber, N., Reichel, M., Zidek, L.M., Kravic, B., Bernkopf, D., von Maltzahn, J., Behrens, J., and Hashemolhosseini, S. (2016).
Wnt/beta-catenin signaling via Axin2 is required for myogenesis and, together with YAP/Taz and Tead1, active in IIa/IIx muscle fibers. Development.

Zhang, Z., Akyildiz, S., Xiao, Y., Gai, Z., An, Y., Behrens, J., Wu, G. (2015).
Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners. Cell Discovery.

Vasileiou, G., Ekici, A.B., Urebe, S., Zweier, C., Hoyer, J., Engels, H., Behrens, J., Reis, A., and Hadjihannas, M.V. (2015).
Chromatin-Remodeling-Factor ARID1 B Represses Wnt/beta-Catenin Signaling. Am. J. Hum. Genet.

Bernkopf, D.B., Hadjihannas, M.V., and Behrens, J. (2015).
Negative-feedback regulation of the Wnt pathway by conductin/axin2 involves insensitivity to upstream signalling. J Cell Sci.

Brauburger, K., Akyildiz, S., Ruppert, J.G., Graeb, M., Bernkopf, D.B., Hadjihannas, M.V., and Behrens, J. (2014).
Adenomatous polyposis coli (APC) membrane recruitment 3, a member of the APC membrane recruitment family of APC-binding proteins, is a positive regulator of Wnt-beta-catenin signalling. The FEBS journal.